Search results for "instrumental variable"

showing 10 items of 32 documents

VARIABLE SELECTION FOR NOISY DATA APPLIED IN PROTEOMICS

2014

International audience; The paper proposes a variable selection method for pro-teomics. It aims at selecting, among a set of proteins, those (named biomarkers) which enable to discriminate between two groups of individuals (healthy and pathological). To this end, data is available for a cohort of individuals: the biological state and a measurement of concentrations for a list of proteins. The proposed approach is based on a Bayesian hierarchical model for the dependencies between biological and instrumental variables. The optimal selection function minimizes the Bayesian risk, that is to say the selected set of variables maximizes the posterior probability. The two main contributions are: (…

0209 industrial biotechnologybusiness.industryComputer scienceInstrumental variablePosterior probabilityBayesian probabilityPattern recognitionFeature selection02 engineering and technology[ SPI.SIGNAL ] Engineering Sciences [physics]/Signal and Image processingLogistic regression01 natural sciences010104 statistics & probability020901 industrial engineering & automationCohortProbability distributionBayesian hierarchical modelingArtificial intelligence0101 mathematicsbusiness[SPI.SIGNAL]Engineering Sciences [physics]/Signal and Image processingSelection (genetic algorithm)[SPI.SIGNAL] Engineering Sciences [physics]/Signal and Image processing
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Stature and long-term labor market outcomes: Evidence using Mendelian randomization.

2017

We use the Young Finns Study (N = ∼2000) on the measured height linked to register-based long-term labor market outcomes. The data contain six age cohorts (ages 3, 6, 9, 12, 15 and 18, in 1980) with the average age of 31.7, in 2001, and with the female share of 54.7. We find that taller people earn higher earnings according to the ordinary least squares (OLS) estimation. The OLS models show that 10 cm of extra height is associated with 13% higher earnings. We use Mendelian randomization, with the genetic score as an instrumental variable (IV) for height to account for potential confounders that are related to socioeconomic background, early life conditions and parental investments, which ar…

0301 basic medicineAdultEmploymentMaleSocial ValuesEconomics Econometrics and Finance (miscellaneous)03 medical and health sciencesYoung Adult0302 clinical medicinestatureMendelian randomizationCovariateEconometricsEconomicsHumans030212 general & internal medicinePoint estimationPersonnel Selectionta512FinlandEstimationta511EarningsSalaries and Fringe BenefitsInstrumental variableConfoundingtyöllisyysheight premiumta3142Mendelian Randomization AnalysisBody Height030104 developmental biologykorkeus8. Economic growthOrdinary least squaresearningsDemographyheightEconomics and human biology
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Does education protect against depression? Evidence from the Young Finns Study using Mendelian randomization

2018

Using participants (N = 1733) drawn from the nationally representative longitudinal Young Finns Study (YFS) we estimate the effect of education on depressive symptoms. In 2007, when the participants were between 30 and 45 years old, they reported their depressive symptoms using a revised version of Beck's Depression Inventory. Education was measured using register information on the highest completed level of education in 2007, which was converted to years of education. To identify a causal relationship between education and depressive symptoms we use an instrumental variables approach (Mendelian randomization, MR) with a genetic risk score as an instrument for years of education. The genet…

0301 basic medicineMaleSYMPTOMSEpidemiologyLOCIGenome-wide association studyVARIANTS0302 clinical medicinekoulutustaustaRisk FactorsMedicine030212 general & internal medicineta515Depression (differential diagnoses)FinlandRISKeducationDepressionInstrumental variableta3142Middle Aged3142 Public health care science environmental and occupational healthOrdinary least squaresdepressionEducational StatusFemaleHEALTHAdultmasennusMODELS03 medical and health scienceskoulutustasoLinear regressionMendelian randomizationMendelian randomizationHumansGENOME-WIDE ASSOCIATIONEstimationta511instrumental variablesbusiness.industryPublic Health Environmental and Occupational HealthsosiaaliepidemiologiaMendelian Randomization AnalysisConfidence interval030104 developmental biology3121 General medicine internal medicine and other clinical medicinebusinessDemographyGenome-Wide Association Study
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2018

The increase in the prevalence of obesity worldwide has led to great interest in the economic consequences of obesity, but valid and powerful instruments for obesity, which are needed to estimate its causal effects, are rare. This paper contributes to the literature by using a novel instrument: genetic risk score, which reflects the predisposition to higher body mass index across many genetic loci. We estimate IV models of the effect of BMI on labor market outcomes using Finnish data that have many strengths: genetic information, measured body mass index, and administrative earnings records that are free of the problems associated with nonresponse, self-reporting error or top-coding. The fi…

2. Zero hungerEarnings030503 health policy & servicesHealth Policy05 social sciencesInstrumental variableCausal effectOverweightmedicine.diseaseObesity03 medical and health sciences0502 economics and business8. Economic growthmedicine050207 economicsmedicine.symptomGenetic risk0305 other medical sciencePsychologyBody mass indexEconomic consequencesDemographyHealth Economics
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Education Leads to a More Physically Active Lifestyle : Evidence Based on Mendelian Randomization

2019

Physical inactivity is a major health risk worldwide. Observational studies suggest that higher education is positively related to physical activity, but it is not clear whether this relationship constitutes a causal effect. Using participants (N = 1651) drawn from the Cardiovascular Risk in Young Finns Study linked to nationwide administrative data from Statistics Finland, this study examined whether educational attainment, measured by years of education, is related to adulthood physical activity in terms of overall physical activity, weekly hours of intensive activity, total steps per day, and aerobic steps per day. We employed ordinary least squares (OLS) models and extended the analysis…

AdultMaleEvidence-based practiceHigher educationregister‐based dataväestötutkimusphysical activityPhysical Therapy Sports Therapy and Rehabilitation030204 cardiovascular system & hematologyliikuntaEducation03 medical and health sciences0302 clinical medicinekoulutustasoMendelian randomizationGlobal healthMendelian randomizationMedicineHumansOrthopedics and Sports MedicineLongitudinal Studies315 Sport and fitness sciencesExerciseLife StyleelämäntapaFinlandväestötietojärjestelmäteducationbusiness.industryInstrumental variable030229 sport sciencesMendelian Randomization AnalysisMiddle Aged3142 Public health care science environmental and occupational healthEducational attainmentCross-Sectional StudieskoulutusOrdinary least squaresObservational studyFemalebusinessfyysinen aktiivisuusDemography
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Intertemporal Substitution in the Spanish Economy: Evidence from Regional Data*

2018

This paper studies the intertemporal substitution in consumption and leisure for the Spanish economy by estimating the first‐order conditions of an individual optimization model with regional and aggregate data. While first‐order conditions determining intertemporal substitution in consumption show a good econometric fit, and the value we obtain for the intertemporal elasticity of substitution is similar to previously available results, the econometric fit of the intertemporal condition in leisure indicates that the behaviour of the Spanish labour supply over the cycle is more complex than can be explained by the canonical intertemporal choice model.

Consumption (economics)Economics and Econometrics050208 financeElasticity of substitution05 social sciencesSubstitution (logic)Instrumental variableIntertemporal choiceEconomyLabour supply0502 economics and businessValue (economics)EconomicsAggregate data050207 economics
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Informal caregiving and work: A high price to pay. The case of Baltic States

2021

Abstract The impact of informal care burden on the labour market outcomes has been the subject of a number of studies. The literature so far has, however, mostly neglected the post-transition countries. The purpose of this study is to provide empirical evidence on various labour market implications of informal care in the three Baltic States – Estonia, Latvia and Lithuania. In particular, we examine the extensive and intensive margins of work, wage effects, job seeking behaviour and utilization of unemployment benefits. We apply instrumental variable approach to address the observed endogeneity of informal care. The obtained results support the existence of a significant deterrent effect of…

Economics and Econometrics030503 health policy & servicesmedia_common.quotation_subject05 social sciencesInstrumental variableWage03 medical and health sciencesWork (electrical)0502 economics and businessUnemploymentEconomicsDemographic economicsEndogeneity050207 economics0305 other medical scienceLife-span and Life-course StudiesEmpirical evidencemedia_commonThe Journal of the Economics of Ageing
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A Spatiotemporal Solution for the Simultaneous Sale Price and Time-on-the-Market Problem

2015

There exists an important methodological challenge when dealing with sale price and time-on-the-market variables because both variables are simultaneously determined and related to the motivation of the sellers and buyers. Exploiting the fact that transactions occur over space and time, we propose a two-stage approach based on instrumental variables (IV) built from information collected from previous transactions. The unidirectional temporal property and the fact that other transactions are exogenous from the perspective of a single buyer or seller are exploited to evaluate the effect of the sale price on time-on-the-market, and the effect of time-on-the-market on the sale price. Based on 2…

Economics and Econometrics050208 financemedia_common.quotation_subjectNegative information05 social sciencesInstrumental variableMicroeconomicsAccounting0502 economics and businessEconomicsQuality (business)050207 economicsMarketingSale priceFinancemedia_commonReal Estate Economics
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Income Inequality and Technology Diffusion: Evidence from Developing Countries*

2011

We study the effect of within-country income inequality on the diffusion of mobile phones using data on market penetration in a sample of developing countries from 1985 to 1998. Mobile phones are an example of international technology, originating in industrialized countries and diffusing worldwide. We find that income inequality, as measured by the income share of the highest earning deciles, has a positive effect on the early diffusion of mobile phones and that the estimated effect becomes greater when a measure of agricultural endowments is used as an instrument. The instrumental variable results are robust to weak instruments. Our findings suggest that the diffusion of new technologies …

Economics and EconometricsEconomic growthInequalityEmerging technologiesmedia_common.quotation_subject05 social sciencesInstrumental variable1. No povertyDeveloping countrySample (statistics)Economic inequality8. Economic growth0502 economics and businessEconomicsDemographic economics050207 economicsDeveloped country050205 econometrics media_commonMarket penetrationScandinavian Journal of Economics
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Maternal Life Satisfaction and Child Outcomes: Are They Related?

2011

This paper investigates the association between maternal life satisfaction and the developmental functioning of two- to three-year-old children as well as the socio-emotional behavior of five- to six-year-old children. We use data from the German Socio-Economic Panel Study (SOEP), which allows us to control for a rich set of child and parental characteristics and to use the mother’s life satisfaction before the birth of her child as an instrument to eliminate potential reverse causality. The results indicate that the more satisfied the mother, the better her child’s verbal skills and the lower his or her socio-emotional problems. The relation is more pronounced for boys than for girls. The …

Economics and EconometricsSociology and Political ScienceLife satisfaction subjective well-being mothers children child development skill formation instrumental variablemedia_common.quotation_subjectLife satisfactionChild developmentjel:I22language.human_languageSocial relationDevelopmental psychologyGermanjel:J13Quality of life (healthcare)Psychological well-beinglanguagePersonalityCognitive skillSubjective well-beingAssociation (psychology)Set (psychology)PsychologyApplied Psychologymedia_common
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